Adaptor Protein 1 Molecular Weight

View protein in prosite ps50003 ph domain 1 hit ps50001 sh2 1 hit.

Adaptor protein 1 molecular weight. Its function in this particular case is yet to be understood. Most adaptor domains display binding specificity for peptide motifs in other signaling proteins that transmit and codify the signals. Adaptor protein 1 ap 1 is a cytosolic heterotetramer involved in the transport of protein cargo from the trans golgi network tgn to endosomes. Ap 1 recruits clathrin to form clathrin coated vesicles and plays a pivotal role in selecting the cargo by recognizing sorting signals in the cytoplasmic tail of integral membrane proteins.

Dj 1 is a redox sensitive adapter protein for high molecular weight complexes involved in regulation of catecholamine homeostasis. The protein has no known catalytic function but has been shown to bind and recruit various proteins involved in the regulation of receptor protein tyrosine kinases. This gene encodes a member of the nck family of adaptor proteins. Nat immunol 6 1020.

It belongs to the iap family of proteins and therefore contains at least one bir baculoviral iap repeat domain ciap1 is a multi functional protein which can be found in the cytoplasm of cells and in the nucleus of tumor cells. The protein contains three sh3 domains and one sh2 domain. Ciap1 also named birc2 is the abbreviation for a human protein cellular inhibitor of apoptosis protein 1. Santambrogio l potolicchio i fessler s.

Ww domain binding protein 2 wbp2 as a binding partner of ww domain protein interacts with several ww domain containing proteins such as yes kinase associated protein yap paired box gene 8 pax8 ww domain containing transcription regulator protein 1 taz and. Signal transducing adaptor protein 1. Ssf55550 ssf55550 1 hit. For example src kinase has a canonical kinase fold as well as a src homology 2 sh2 domain that bind to specific phosphotyrosine residues on activated receptors and a src homology 3 sh3 domain that binds to polyproline pro x x pro motifs.

The ww domain is composed of 38 to 40 semi conserved amino acids shared with structural regulatory and signaling proteins. It was first isolated in 1986 by stevenson and goodenough using a monoclonal. Stem cell adaptor protein 1. View protein in pfam pf00169 ph 1 hit pf00017 sh2 1 hit.

Zonula occludens 1 zo 1 also known as tight junction protein 1 is a 220 kd peripheral membrane protein that is encoded by the tjp1 gene in humans. National institutes of health the european molecular biology laboratory state secretariat for education research and innovation seri.